State-dependent microstructural white matter changes in bipolar I depression
نویسندگان
چکیده
منابع مشابه
White matter microstructural abnormalities in euthymic bipolar disorder.
BACKGROUND Abnormal diffusion parameters are reported in specific brain regions and white matter tracts in bipolar disorder. AIMS To investigate whether these abnormalities are generalised, and thus evident in large regions of white matter. METHOD Diffusion parameters were measured at several regions in the corpus callosum and in deep/periventricular white matter in 28 currently euthymic pa...
متن کاملMicrostructural Changes of Anterior Corona Radiata in Bipolar Depression
OBJECTIVE In bipolar disorder, dysregulation of mood may result from white matter abnormalities that change fiber tract length and fiber density. There are few studies evaluating the white matter microstructural changes in bipolar I patients (BD) with depressive episodes. The present study aimed to evaluate anterior corona radiata in BD patients with depressive episode using Diffusion Tensor Im...
متن کاملLongitudinal changes in microstructural white matter metrics in Alzheimer's disease
BACKGROUND Alzheimer's disease (AD) is a progressive neurodegenerative disorder. Current avenues of AD research focus on pre-symptomatic biomarkers that will assist with early diagnosis of AD. The majority of magnetic resonance imaging (MRI) based biomarker research to date has focused on neuronal loss in grey matter and there is a paucity of research on white matter. METHODS Longitudinal DTI...
متن کاملWhite matter microstructural impairments and genetic liability to familial bipolar I disorder.
BACKGROUND Subtle abnormalities in frontal white matter have been reported in bipolar disorder. AIMS To assess whether impaired integrity of white matter tracts is associated with bipolar disorder and genetic liability for the disorder. METHOD A total of 19 patients with psychotic bipolar I disorder from multiply affected families, 21 unaffected first-degree relatives and 18 comparison indi...
متن کاملMicrostructural white matter abnormalities and remission of geriatric depression.
OBJECTIVE White matter abnormalities may interfere with limbic cortical balance and lead to chronic depressive syndromes. The authors used diffusion tensor imaging to test the hypothesis that depressed elders who fail to achieve remission have microstructural white matter abnormalities in cortico-striato-limbic networks implicated in geriatric depression. METHOD The subjects were nondemented ...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: European Archives of Psychiatry and Clinical Neuroscience
سال: 2009
ISSN: 0940-1334,1433-8491
DOI: 10.1007/s00406-009-0002-8